|Other names||β-Phenyl-γ-aminobutyric acid, fenibut, phenybut, beta-phenyl-GABA, Beta-phenyl-gamma-aminobutyric acid, 4-Amino-3-phenylbutyric acid HCl,Noofen,|
|Molecular Formula||C10H13NO2 C10H15NO2Cl|
|Molecular Weight||179.216; 215.58|
|Appearance/Color||White crystalline powder|
|Dosage||250–1500 mg, twice daily|
|Applied industries||nootropic supplements,pharmaceuticals,drugs,medicines|
What is phenibut?
Phenibut, also known as beta-Phenyl-gamma-aminobutyric acid (beta-phenyl-GABA), according to Wikipedia, is a derivative of GABA, a neurotransmitter that crosses the blood-brain barrier. Unlike GABA, because of the added phenyl group, phenibut is able to easily cross the blood brain barrier, and can consequently exert its functions more effectively on the brain. It has been reported that phenibut is able to improve mental performance as well as reduce anxiety and improve sleep. Phenibut has many other popular names, such as (RS)-4-amino-3-phenyl-butyric acid, fenibut, phenybut, etc. Phenibut is sold as dietary supplement in two forms currently, the HCl and Free Amino Acid, just like arginine hcl and arginine base. Hcl form is usually more stable in general. Phenibut is also sold in raw powder or dispensed in capsules for easier dosing.
Phenibut is increasingly popular among end consumers since more people have health problems with mood, memory, sleep and other mental conditions every day. It is usually used as a single supplement or stacked with other similar ingredients, such as herbal extracts 5-htp, Valerian Root, St John’s wort, Huperzine A, or nootropics such as Alpha GPC, picamilon, etc.
How does phenibut work?
The mechanism of action of phenibut is relatively simple. How does Phenibut work to promote better mood, stress relief and alleviate anxiety? Also, what is the basis behind the nootropic effects of this supplement? Phenibut is present in the body as a product of the major inhibitory neurotransmitter – GABA -aminobutyric acid.
Phenibut exerts its mechanism of action as a very potent GABA agonist (GABA-mimetic), which results in a plethora of GABA-like effects at varying dosages, including as an anxiolytic (anti-anxiety), nootropic (cognition enhancing) and hypnotic (sleep-inducing) agent. Phenibut also stimulates dopamine receptors and antagonizes beta-phenylethylamine (PEA).
As compared to Baclofen and valium (diazepam), Phenibut is known for its calming effects and for its ability to serve as an anti-stress and anti-anxiety to the body. Phenibut, apart from being neuroprotective, also helps in the reduction of induced loss of memory (amnesia) and aids smooth night sleep.
Benefits of taking phenibut supplements
henibut has been using as an anti-depression ingredient in many dietary supplement formulas, and its main benefits include help better sleep and mood, reduce stress and anxiety, good for the well of being,etc.
Phenibut Benefits for Sleep
The most commonly application for phenibut over the recent years is its use as an anti-anxiety drug and sleeping aid. It has been well documented that phenibut improves sleep quality and duration as well as having a calming effect that is not a result of sedative effects. Such calming and improved sleep as a result of phenibut supplementation may be beneficial for bodybuilders as growth hormone is secreted during periods of deep sleep, while sleep and rest is also very important for a recover.
Phenibut Benefits for Mental Performance
Animal studies have shown that mice given phenibut resulted in significantly improved reaction times when given a stimulus to respond to. Furthermore, treated animals performed better at other mental performance tests.
Phenibut and reduce anxiety benefits
Phenibut is one of the nootropics consistently rated as the best for dealing with anxiety and depression. It offers a lot of anxiolytic benefits, reducing stress and improving your mood and emotional well-being. Many people take it as a sleep aid or to help them relax and decompress during periods of high anxiety and nervousness. Phenibut works so well for this condition that it has even been endorsed by the Russian government, which is where it was developed.
Phenibut Benefits for Feelings of Wellbeing
Dopamine is a hormone that is responsible for feelings of wellness and joy, especially after an accomplishment. Phenibut is known to stimulate dopamine receptors (Lapin, 2001), which may result in similar feelings of general wellbeing. Animal studies showed that rabbits showed better signs of coping when challenged with emotionally negative situations after given phenibut. Thus, phenibut may be a helpful supplement during periods of stress.
dosage control is particularly important with a compound as strong as Phenibut. The recommended dosage range is between 250 mg to 1000 mg but you should start with a smaller Phenibut dose and allow your body time to adjust before increasing to the full amount. This compound has a much longer half-life than other nootropics and the effects can last for a full day. For this reason, you will probably not want to take more than one Phenibut dosage in a day with at least 4-6 hours between any follow-up administrations. Phenibut HCL is water soluble and the powdered form of the supplement can be easily mixed into water or juice for ingestion. However, because the powder can taste quite sour many people prefer to cap their own pills after buying the bulk powder which is both cost-effective and convenient.
Herb Nutritionals Co., Ltd is a raw material manufacturer and supplier of sports nutrition ingredients and nootropics is one of our latest product lines since these three years. If you need more information of phenibut regarding certificate of analysis (COA), price quotation, quality concerns,MSDS, shipping issues, you are welcome to write to us by email, and we will respond within 12 hours.