Picamilon is often in the form of picamilon sodium salt, and is a mood enhancer against depression, improve mental performance, treat anxiety as anxiolytics
|Product name||Picamilon sodium salt|
|Synonyms||Pycamilon, nicotinoyl-GABA, pikamilon, 4-(Pyridine-3-carbonylamino)butanoic acid , nicotinyl-y-aminobutyric acid, picamilone, N-Nicotinoyl, НПК ЭХО,picamilon sodium salt, picamilion|
62936-56-5 (sodium salt)
|Appearance/color||White to off white crystalline powder|
|dosage||20-50mg per serving, taken 2-3 times per day|
What is picamilon?
Picamilon is a dietary supplement ingredient used as a brain enhancer and anxiolytic for relieving anxieties, and has many names and in different forms. In order to make the best reviews of picamilon to those who come across it, we begin with its names and forms. Picamilon is often misspelled as pikamilon, picamilion, picamilone,and pycamilon. Since picamilon was first invented in the Soviet Union in the early 1970s, it is not strange to have so many variations of picamilon names translated from Russian language to English. However, picamilon is the most popular word used in dietary supplement formulas.
Chemical speaking, picamilon is a combination of niacin (a kind of Vitamin B3) and Gamma Amino Acid Butyric Acid(AKA GABA, the most popular neurotransmitter). In this way, picamilon is also called nicotinoyl-GABA, nicotinyl-y-aminobutyric acid or just N-Nicotinoyl. Niacin is known to promote widening of the blood vessels, while gamma-aminobutyric acid plays a key role in regulating nervous system activity. Moreover, picamilon is more potent than niacin and GABA since picamilon crosses the blood-brain barrier easily.
From Wikipedia, the CAS number of picamilon is 34562-97-5. And there is also picamilon sodium salt from on the market with CAS No. 62936-56-5. These are the two main forms of picamilon, in powder, tablet, and in capsules.
Mechanism of action of picamilon
How does picamilon work? The act of modes is simple. As stated before, picamilon is the biochemical combination of niacin and GABA, the majority of its benefits are derived from GABA and niacin. When picamilon crosses the blood-brain barrier, it breaks down or hydrolyzed into niacin and GABA. From here, the effects produced by Picamilon are typical of higher levels of GABA and niacin. And the mechanism of picamilon are the mechanisms of niasin and GABA..
GABA is a neurotransmitter responsible for carrying information from one cell to another. Research suggests that people with certain mental health concerns (including serious depressive disorder and anxiety) may be more likely to have low levels of GABA.
The released GABA theoretically would activate GABA receptors potentially producing an anxiolytic response. The released niacin enables to enhance brain blood circulation through its vasodilatory properties while is an inhibitory neurotransmitter that contributes a calming effect. As a strong vasodilator, picamilon is likely to be helpful for the remedy for migraine headaches.
Picamilon VS phenibut
When we talk of picamilon, we have to mention another ingredient-phenibut. Both picamilon and phenibut are derivatives of the neurotransmitter GABA. Phenibut is more popular known to the dietary industries, and easily accessible and available freely online, whereas there is little information about Picamilon.
As a pure anxiety-removing and mood boosting medicine or supplement, Phenibut is claimed to be better than picamilon, and it has no negative effects either. However, picamilon also elevates learning and memory and is probably a bit more effective than Phenibut for this function.
Benefits of Picamilon
Picamilon is among the list of best regarded nootropics for anxiety relaxation, mental performance, and anti-aging effects. Picamilon can be utilized for mood enhancement, cognitive energy,awareness, mental alertness, stress, anxiety, relaxation, and also to help counteract the mood disturbances (irritability) that is commonly involved with dieting.
picamilon is said to help treat the following conditions:
•anxiety (including social anxiety)
•high blood pressure
Picamilon side effects
Due to a lack of research, little is known about the adverse effects of regular use of picamilon. However, there’s some concern that picamilon may trigger a number of side effects, such as headache, tingling, and nausea. Picamilon may interact with certain medications, such as benzodiazepines.
Picamilon is said to be very safe and unlikely to present problems when used in appropriate dosages of less than 500 mg per day. Compared to other anxiolytics, Picamilon is less likely to present problems related to tolerance, withdrawal, addiction to abuse. However, these are all still possibilities which is why you should ideally take this supplement only under doctor supervision.
Typically, individuals who take Picamilon use anywhere from 50-300 mg daily split over several administrations. In most cases, people would rather divide the administrations into a morning and an evening dose. It is advisable to supplement Picamilon on an empty stomach, and based on your preference, you can buy it in powder, tablet or encapsulated form. The effects range from two to four hours, but it has been confirmed that Kava and Valerian have the possibilities to enhance these effects.
Where to buy picamilon raw ingredient?
Picamilon raw materials from Herb Nutritionals co., ltd is increasingly popular among our clients in the UK, Canada, United States and other countries in Europe. Phenibut is also a hot selling product among who bought picamilon from us. Information on picamon pricing, COA, MSDS is all available upon your request by mail or phone.