Hordenine hcl 99%
Hordenine hcl is a mild stimulant used in pre workout supplements, beneficial to energy boost and weight loss.
Hordenine hcl powder
|Product name||hordenine hcl|
|synonyms||N,N-dimethyltyramine, hordenine hydrochloride, хорденин,4-(2-Dimethylaminoethyl)phenol ,N,N-dimethyl-4-hydroxy-phenethylamine|
|CAS number||6027-23-2(hcl form), 3595-05-9(hordenine base)|
|Half life||3-5 hours|
|Benefits||Boost energy, stimulant, lose weight|
|dosage||50-400 mg 2-3 times a day.|
|applications||Sports nutrition, pre workout supplements|
What is hordenine hcl?
Hordenine hcl is a natural nutritional supplement best known to the bodybuilding industry for its mild stimulant effects as a DMAA replacement. Hordenine hcl also has the promising prospects for burning fat and supplying extra energy throughout pre workout in the gym.
Hordenine hcl is chemically related to N-methyltyramine, both are central nervous system stimulant sharing the well-known biogenic amine tyramine and some pharmacological properties.
Source of hordenine
According to Wikipedia, hordenine is part of the alkaloid family of the phenylethylamine (aka PEA) detected in many plants, such as the roots of sprouted barley extract, bitter orange fruit, cactus Anhalonium fissuratum, Senecio scandens, Pancratium maritimum, Lophophora williamsii, Polyalthia longifolia, etc. However, barley is the best source for bulk quantity of commercial hordenine hcl.
Chemically speaking, hordenine hcl and hordenine base are two different products since the CAS number of hordenine hcl is 6027-23-2 while CAS number for hordenine base is 3595-05-9, although their applications are quite similar. Hordenine HCL form is more water soluble and more easily absorbed by the body due to its acidic character; thus making it more popular among supplements manufacturers. If not specified, the below term “hordenine” is actually referring to “hordenine hcl” for the sake of convenience.
Mechanism of action of hordenine hcl
How does hordenine hcl work? Hordenine works as a central nervous system stimulant. Hordenine is a mild MAO-B inhibitor. MAO-B is an enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This enzyme preferentially degrades benzylamine and phenylethylamine. Like MAO-A, MAO-B also degrades dopamine. Usually this degradation function of MAO-B is negative for pre-workout ingredients. With this MAO-B inhibiting ability, Hordenine HCl may prevent stimulant tolerance by decreasing the effect of monoamine oxidase, thus hordenine HCl can prevent the breakdown of many stimulants and make them more effective.
In addition, hordenine is said to work by slowing the digestion of food, and stimulating the release of the hormone norepinephrine, which can help energize the body.
Benefits of taking hordenine hcl
The main benefits of hordenine hcl are classified in two categories: one is as a stimulant and the other is for weight loss. In this way, spin-off benefits of hordenine are that metabolism is enhanced and optimal energy is promoted. Hordenine may also affect stress levels, mood, sleep, memory and more.
Hordenine as a stimulant
Hordenine hcl is a legal stimulant and supplies extra energy to the body cells, enhancing athlete performance. Hordenine hcl mimics the effects of adrenaline while also acting centrally in the brain to decrease the reuptake of Norepinephrine, which produces a clean and noticeable increase in focus, energy and stimulation, all without the usual crash associated with caffeine containing energy products. Hordenine may also act on the MAO (Mono Amine Oxidase) system, preventing the breakdown of neurotransmitters such as Phenylethylamine, also known as the Love chemical. With hordenine, you can harness the stimulating power of your own mind, increasing focus, concentration and energy to power through tough workouts or long days at the office. Compared to Caffeine, Hordenine delivers a much smoother, longer-lasting stimulating effect, with zero crash at the end of the day.
hordenine and weight loss
The main benefit of hordenine is its potential to assist in the release of fat from fat cells for energy. Hordenine stimulates the release of norepinephrine. Norepinephrine is an excitatory hormone that energizes the body. It’s lipolytic, it liberates lipids from adipose tissue. When this occurs, liberated lipids are oxidized for energy, and this results in an overall reduction of body fat.
Studies have indicated that hordenine may increase metabolism, leading to the higher processing and reduction of fat.
Hordenine and Appetite Control
Users report that it is helpful in appetite control, thought to act as a powerful appetite suppressant. Many scientists feel that part of the working of Hordenine HCL involves actually slowing down the metabolism and digestion of food. As both of these factors slow down, it becomes easier to last longer between meals and food cravings tend to be reduced. Therefore, you take longer time to feel hungry.
Dosage of Hordenine HCL
Users typically take Hordenine multiple times a day to maintain its effect. A dose of about 25 mg three times a day is a good start. Some people find Hordenine dosages works best with the addition of PEA, caffeine anhydrous, or yohimbine. Hordenine is typically sold in capsule form, stacked with other amino acids or herbal extracts is a good choice.
Side Effects of Hordenine hcl
Hordenine hcl is generally safe when properly dosed. side effects only occurred after a high dose or overdose of the compound was taken. Common syndromes or symptoms of the adverse effects such as nausea, insomnia, dizziness, anxiety, upset stomach and mood swings are derived from its stimulatory effects. Blood pressure may rises as well, and those with heart conditions should not use the compound.
Where to buy best quality hordenine hcl powder?
Hordenine hcl is among the list of our stimulant ingredients used in bodybuilding pre workouts supplements. If want to know more information regarding certificate of analysis (COA), pricing, stock availability, production scale of our hordenine hcl, please kindly contact us via email or direct phone call.